Research Publications Back
Utpal Bhadra Group`s Publications
|Click here for team members
Title Journal Year
microRNAs: Cutting edge weapons in our drug arsenal (Review)Research Matters ( new agencies)2017
Insulin/insulin-like growth factor signalling (IIS) based regulation of lifespan in cross speciesBiogerontology doi10.1007/s10522-016-9670-8.2017
Down-regulation of BORIS/CTCFL efficiently regulates cancer stemness and metastasis in MYCN amplified Neuroblastoma cell line by modulating Wnt/β-Catenin signaling pathwayBioche and Biophy, Res. Com doi 10.1016/J.bbrc 2017.01.0062017
Running GAGA factors towards fly development.PeertechZ J of biological Research and Development 2(1)004-0011 2017
The Drosophila gene maleless counteracts the X-chromosome mediated global aneuploid effects in males. Human Frontier Sci. Prog.Selected in 15 coutries Article Awardee (website) 2016
Insulin/insulin-like growth factor signalling (IIS) based regulation of lifespan in cross speciesBiogerontology (in press)2016
Small molecule modulators of micro-RNA and their role in cancer therapyBiotechnology and Biomedical engineering (in press)2016
Prohibitin confers cytopretection against ISO-induced hypertrophy in H9c2 cells via attenuation of oxidative stress and modulation of Akt/Gsk-3β signallingMolecular and cellular Biochemistry (in press)2016
Small RNA, big impact and robust hope: Biochemical basis for RNA interferenceIn Book `Basic Biochemistry` edited by Dr. Wahid Ali Khan. Austin Publishing Group new Jersey, USA ( In press)2016
Simultaneous delivery of Paclitaxel and Bcl-2 siRNA via pH sensitive liposomal nancarrier for the synergistic treatment of melanomaScientific Reports doi: 10.1038/srep352232016
Pigmy MicroRNA: surveillance cops in therapy kingdom Molecular Medicine doi: 10.2119/molmed.2016.001362016
Novel SAHA analogues inhibit HDACs, induce apoptosis and modulate the expression of microRNAs in Hepatocellular carcinomaApoptosis 21:269-282 DOI: 10.1007/s10495-015-1206-12016
Drosophila maleless gene counteracts X global aneuploid effects in males.FEBS J doi: 10.1111/febs.13818 2016
miR-15a/miR-16 induces mitochondrial dependent apoptosis in breast cancer cells by suppressing oncogene BMI1. Life Science doi:10.1016/j.lfs.2016.08.028 2016
Glioma Amplified Sequences 41(Gas41): a vinculum between RNAi and Glioma American Journal of Cancer Research ( In Press) 2016
RNA twister and new spreading component in dosage compensation winds Frontier in cell and Dev elopmental Biology (Nature publisher) ( In press)) 2016
Regulation of cell proliferation and migration by miR-203 via GAS41/miR-10b axis in human glioblastoma cells.Plos One 11(7): e0159092. doi:10.1371/journal. pone.0159092 2016
RNA interference (RNAi) as a metronome of the circadian cadence.J. Mol. Biol. 5:3 (
Evolutionary shift of X aneuploid targets from X to autosome and their dose dependent expression are mitigated by maleless geneFEBS Journal doi:10.1111/febs.13818.2016
Restoring Mitochondrial Function: A Small molecule Mediated Approach to Enhance Glucose Stimulated Insulin Secretion in Cholesterol Accumulated Pancreatic beta cells.Nature Scientific Reports 6:27513 DOI: 10.1038/srep27513 2016
Non coding RNA and epigenomic clouds in insulin and longevity skiesFrontiers in Aging Neuroscience (In Press)2016
A novel Bisindole - PBD conjugate inhibits angiogenesis by regulating STAT3 and VEGF in breast cancer cells.Life Sciences DOI: 10.1016/j.lfs.2016.03.0242016
Get well in the RNAi way-RNAi, a billion dollar baby in therapyJ. Mol. Biol. 5: 158. doi:10.4172/2168-9547.1000158 2016
Long non- coding RNAs are frontier breakthrough of RNA world and RNAi based gene regulation. In Book InTech (Open Science and Open Minds) RNA Interference Editor I.Y. Abdurakhmonov. Chapter 4: p63-87.2016
Argonaute-1 machinery silent cancer noises. J. Cancer Surgery 1: 102. doi:10.4172/cns.10001022016
Long Non-Coding RNA: functional agent for disease traitsRNA Biology DOI: 10.1080/15476286.2016.1172756 2016
Tiny microRNAs fine-tune Amyotrophic Lateral Sclerosis (ALS) regulationIn Book InTech (Open Science and Open Minds) Novel Aspects of Amyotrophic Lateral Sclerosis. Editor: Humberto Foyaca Sibat Chapter 8 pp 135-1622016
Drosophila MOF Regulates DIAP1 and Induces Apoptosis in a JNK Dependent PathwayApoptosis 21:269-282 DOI: 10.1007/s10495-015-1206-1 2016
Novel Etoposide analogue modulates expression of angiogenesis associated microRNAs and regulates cell proliferation by targeting STAT3 in breast cancer.Plos One 10(11):e0142006. doi: 10.1371/journal.pone.0142006. 2015
RNAi : Cell Defense of Host.Springer Verlag and McMillan Production (Springer Nature) (In Press).2015
Different types of transgene silencing in animals: a natural foundation for RNAi technology.Molecular Biology journal 4: 137. doi:10.4172/2168-9547.1000137.2015
HDAC inhibitor misprocesses bantam oncomiRNA, but stimulates hid induced apoptotic pathway.Nature Scientific Reports 5:14747 DOI: 10.1038/srep14747 2015
Para amino benzoic acid derived self assembled biocompatible nanoparticles for efficient delivery of siRNA.International Journal of Nanomedicine 10: 6411-24. doi: 10.2147/IJN.S86238.2015
SIRT inhibitors, Bisindole - PBD modulate apoptosis in breast cancer cellsCancer Biology and Therapy 16(10): 1486-501. doi: 10.1080/15384047.2015.10717312015
Computational approach for elucidating interactions of cross-species miRNAs and their targets in Flaviviruses Journal of Vector Borne Diseases (JVBD) 52: 11-22 2015
A Spatio-temporal Cardiomyocyte Targeted Vector System for Efficient Delivery of Therapeutic Payloads to Regress Cardiac Hypertrophy Abating Bystander Effect. Journal of Controlled Release 200: 167-1782015
PABA Nanoparticles as Effective Delivery Agents of siRNAs into Biological Systems. In Book: `Nanoscience & Technology for Mankind`. Eds: Ashok Misra, M.G.K. Menon. In: The National Academy of Sciences, India, pp.96-110. 2015
Drosophila oncogene Gas41 is a RNAi modulator that intersects heterochromatin and siRNA pathwayFEBS Journal 282: 153-1732015
Uncoupling of X-linked gene silencing from XIST binding by DICER1 and chromatin modulation on human inactive X chromosome Chromosoma 124(2):249-62. 2015
A Complex genome-microRNA interplay in Human mitochondria BioMed Research International (JBB)Volume 2015, Article ID 206382, 13 pages 2014
miR-15/16 complex targets p70S6 kinase 1 and controls cell proliferation in MDA-MB-231 breast cancer cells. Gene 552: 255-264. 2014
Organic Nanotubes: Promising Vehicles for Drug Delivery In Book: `Application of Nanotechnology in Drug Discovery` Eds: Prof All Demir Sezer. InTech Open Science/Open Minds - Chapter 13: p447-468 (ISBN 978-953-51-1628-8; DOI: 10.5772/58412) 2014
Big from small: microRNA tale in animal. In Book: `Trends in Animal Biotechnology` Editor S.K. Gautam, Published by International Press Corporation, USA (In press) 2014
A novel bisindole-PBD conjugate causes DNA damage induced apoptosis via inhibition of DNA repair pathway. Cancer Biology & Therapy 15:10-17 2014
microRNA gene interaction in Amyotrophic Lateral Sclerosis dataset. Dataset papers in Science 2014
Argonaute-1 functions as cell cycle check point protein by controlling Cyclin B in Drosophila melanogaster. FASEB Journal 28: 655-666. 2014
A complex network of microRNAs expressed in brain and genes associated with Amyotrophic Lateral Sclerosis (ALS). International Journal of Genomics 2013; Article ID 383024, 383024. 2014
Quinazolino linked 4β-amidopodophyllotoxin conjugates regulate angiogenic pathway and control breast cancer cell proliferation. Bioorg Med Chem. 21(21): 6414-26. doi: 10.1016/j.bmc.2013.08.051 2013
Novel anthranilamide-pyrazolo[1,5-a]pyrimidine conjugates modulate the expression of p53-MYCN associated micro RNAs in neuroblastoma cells and cause cell cycle arrest and apoptosis, Bioorg Med Chem Lett 15;23(20):5699-706. doi: 10.1016/j.bmcl.2013.08.018 2013
Drosophila MOF controls Checkpoint protein2 and regulates genomic stability during early embryogenesis. BMC Mol Biol. 14:1. doi: 10.1186/1471-2199-14-1. 2013
Imidazo-benzothiazoles a potent microRNA modulator involved in cell proliferation. Bioorg Med Chem Lett. 22: 6418-6424. 2012
Plant HDAC inhibitor chrysin arrest cell growth and induce p21WAF-1 by altering chromatin of STAT response element in A375 cells. BMC Cancer 12(1):180 2012
Drosophila Ago-1 is critical for transcriptional cosuppression and heterochromatin formation Chromosome Research 20(3):333-351 2012
aza-Flavanones as potent cross-species microRNA inhibitors that arrest cell cycle. Bioorg. Med. Chem. Lett. 22(1):645-648 2012
The role of MOF in the ionizing radiation response is conserved in Drosophila melanogaster Chromosoma 121(1):79-90 2012
Effect of Benzothiazole based conjugates in causing apoptosis by Regulating p53, PTEN and MAP Kinase proteins affecting miR-195a and miR-101-1 Cancer Cell (Int.) 11(1):36 2011
The RNA helicase Rm62 cooperates with SU(VAR)3-9 to re-silence active transcription in Drosophila melanogasterPLoS One 6(6):e207612011
Chalcone-imidazolone conjugates induce apoptosis through DNA damage pathway by affecting telomeresCancer Cell Int. 11:112011
Sub-cellular internalization and organ specific oral delivery of PABA nanoparticles by side chain variationJl of Nanobiotechnology 9:102011
Target sites for microRNA expressed in pancreatic islets in Type 2 diabetes mellitus associated genes. Online J. Bioinformatics 11: 224-243 2010
4-N-Pyridin-2-yl-benzamide nanotubes compatible to mouse stem cell and oral delivery in DrosophilaNanotechnology 21: 155102 doi: 10.1088/0957-4484/21/15/155102 2010
MOF and histone H4 acetylation at lysine 16 are critical for DNA Damage Response and DSB Repair Mol. Cell. Biol. 30: 3582–3595. 2010
microRNA Tales in Fly Development: In Book "Regulation of Gene Expression by Small RNAs" Eds J.J. Rossi and R.K. GaurIn Book CRC Press, California, USA, pp123-1482009
Interaction map and selection of microRNA targets in Parkinson`s disease related genesJournal of Biomedicine & Biotechnology Article ID 363145, 11pages DoI 10,1155/2009/3631452009
MicroRNAs - micro in size but macro in functionFEBS J. 275: 4929-44442008
Development of Novel Pyrrolo[2,1-c][1,4]Benzodiazepine ?-Galactoside Prodrugs for Selective Therapy of Cancer by ADEPT and PMTChem Med Chem 3: 794-8022008
Histone H3 methylation is an epigenetic imprint for alcohol induced liver injuryLife Sciences 81: 979-9872007
Histone H3 methylation is an epigenetic imprint for alcohol induced liver injury Life Sciences 81: 979-987 2007
RNAi components are required for nuclear clustering of Polycomb group response elementsCell 124 : 957-9712006
Misregulation of Sex-lethal and disruption of MSL complex localization in Drosophila species hybridsGenetics 174: 1151-11592006
Interrelationship between transcriptional and post- transcriptional silencingIn Book Proceedings in Cold Spring Harbor Symposium 69: 433-438.2005
MSL complex insulates the response of Histone modifiers to x-linked genes in malesGenetics 169: 2061-20742005
Heterochromatin Silencing and HP1 localization in Drosophila are dependent on the RNAi machineryScience 303: 669-6722004
Role of trans-acting dosage modifiers in X chromosomal dosage compensationGenetica 117: 179-1902003
Transgene cosuppression in DrosophilaIn Book `Gene Silencing` Eds. Gregory Hannon, In Book Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York pp23-432003
RNAi related mechanisms affect both transcriptional and post-transcriptional transgene silencing in DrosophilaMolecular Cell 9: 315-323 2002
Dosage dependent gene regulation in multicellular eukaryotes: dosage compensation, aneuploid syndromes and polygenic quantitative traitsDevelopmental Biology 234: 275-2882001
Histone acetylation and gene expression of Sex-lethal mutants in DrosophilaGenetics 155: 753-7632000
Making noise about silence : Repression of Repeated genes in animalsCurr. Opin. Genes Dev. 10: 211-2162000
Histone acetylation and gene expression of Sex-lethal mutants in Drosophila.Genetics 155: 753-763 (IF: 4.242).2000
Cosuppression in nonhomologous transgenes involves mutually related endogenous sequencesCell 99: 35-46 (IF: 32.401).1999
Less from More: cosuppression of transposable elements.. Nature Genetics 21: 148-151 (IF: 36.377)1999
Role of male specific lethal genes in modifying the effects of sex chromosomal dosage in Drosophila. Genetics 152: 249-168 (IF: 4.242).1999
Interaction among dosage dependent trans-acting modifiers of gene expression and position effect variegation in Drosophila.Genetics 150: 251-263 (IF: 4.242).1998
Role of multiple trans-acting regulators in modifying the effect of the retrotransposon, copia, on host gene expression in Drosophila. Mol. Gen. Genet. 259: 198-206 (IF: 2.453).1998
Cosuppression in Drosophila: gene silencing of Alcohol dehydrogenase gene by white-Adh transgenes is Polycomb dependent.Cell 90: 479-490 (IF: 36.377).1997
A sex-influenced modifier in Drosophila that affects a broad spectrum of target loci including the histone repeats. Genetics 146: 903-917 (IF: 4.242).1997
A trans-acting modifier causing extensive overexpression of genes in Drosophila melanogaster. Mol. Gen. Genet. (Berl.) 254 : 621-634 (IF: 2.453)1997
Characterization of a sex influenced modifier of gene expression and suppressor of position-effect variegation in DrosophilaMol. Gen. Genet. (Berl.) 250: 601-613 (IF: 2.453)1996
Useful Links Related Links Campuses
Copyright 2010 © CCMB, Uppal Road, Hyderabad 500007, AP, India