CCMB

CSIR - Centre for Cellular & Molecular Biology

The Innovation Engine of India

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The facility offers a large panel of state-of-the-art equipment to address queries regarding the structures, folding/stability, and interactions of biomolecules. Proper hands-on training is provided to users, and equipment time may be booked around the clock by mail to the Business Development Group (BDG) or through the AnalytiCSIR portal (for academic and industrial users). The BCF is managed by a PhD scientist who assists researchers in the design, implementation, and analysis of experiments and results. In addition, the instrumentation division of the CSIR-CCMB supports the maintenance and repair of various instruments, which reduces the downtime of instruments.

The BCF is equipped with spectroscopic and calorimetric instruments for the study of structure, folding, binding thermodynamics and kinetics, and quantitation experiments. For biomolecular interactions, BCF offers multiple calorimetric instruments such as PEAQITC, ITC200, VP-ITC, and VP-DSC, and new instruments such as Nano Temper Monolith. N115

To determine the secondary structure, the facility features a Jasco J-815 circular dichroism spectrometer with Peltier-based temperature control, a Horiba dynamic light scattering (DLS) instrument for quick molecular size characterization, zeta potential, and Brucker’s Alpha FT-IR spectrometer for powdered samples. Various high-end fluorometers are available to measure the fluorescence lifetime as well as regular excitation/emission spectra. The complete list of instruments is as follows:

The facility offers a large panel of state-of-the-art equipment to address queries regarding the structures, folding/stability, and interactions of biomolecules. Proper hands-on training is provided to users, and equipment time may be booked around the clock by mail to the Business Development Group (BDG) or through the AnalytiCSIR portal (for academic and industrial users). The BCF is managed by a PhD scientist who assists researchers in the design, implementation, and analysis of experiments and results. In addition, the instrumentation division of the CSIR-CCMB supports the maintenance and repair of various instruments, which reduces the downtime of instruments.

  1. Horiba Dynamic Light Scattering (DLS) particle Size analyzer
  2. Nano temper Monolith. N115 Green/Red Instrument

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